TECHNOLOGY REPORT Cre-Mediated Recombination in the Pituitary Gland
نویسندگان
چکیده
Lisa J. Cushman, Heather L. Burrows, Audrey F. Seasholtz, Mark Lewandoski, Nicholas Muzyczka, and Sally A. Camper* Department of Human Genetics, University of Michigan, Ann Arbor, Michigan Program in Cellular and Molecular Biology, University of Michigan, Ann Arbor, Michigan Mental Health Research Institute and Department of Biochemistry, University of Michigan, Ann Arbor, Michigan Department of Developmental Biology, University of California, San Francisco, California Department of Molecular Genetics and Microbiology, University of Florida, Gainesville, Florida
منابع مشابه
TECHNOLOGY REPORT Cre-Mediated Recombination in Pituitary Somatotropes
We report a transgenic line with highly penetrant cre recombinase activity in the somatotrope cells of the anterior pituitary gland. Expression of the cre transgene is under the control of the locus control region of the human growth hormone gene cluster and the rat growth hormone promoter. Cre recombinase activity was assessed with two different lacZ reporter genes that require excision of a f...
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